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Article

Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor.

Nature - 2 Nov 2006

Ben-Chaim Yair, Chanda Baron, Dascal Nathan, Bezanilla Francisco, Parnas Itzchak, Parnas Hanna

Abstract excerpt

Activation by agonist binding of G-protein-coupled receptors (GPCRs) controls most signal transduction processes. Although these receptors span the cell membrane, they are not considered to be voltage sensitive. Recently it was shown that both the activity of GPCRs and their affinity towards agon...

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Source

Identifiers

PMID: 17065983
DOI: 10.1038/nature05259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17065983-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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