Article
Charge scan reveals an extended region at the intracellular end of the GABA receptor pore that can influence ion selectivity.
The Journal of general physiology - 1 Jan 2008
Wotring Virginia E, Weiss David S
Abstract excerpt
Selective permeability is a fundamental property of ion channels. The Cys-loop receptor superfamily is composed of both excitatory (ACh, 5-HT) and inhibitory (GABA, glycine) neurotransmitter-operated ion channels. In the GABA receptor, it has been previously shown that the charge selectivity of t...
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