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Article

Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice.

Cytoskeleton (Hoboken, N.J.) - 1 Sept 2015

Li Linjing, Rao Kollu Nageswara, Zheng-Le Yun, Hurd Toby W, Lillo Concepción, Khanna Hemant

Abstract excerpt

Degeneration of photoreceptors (rods and cones) results in blindness. As we rely almost entirely on our daytime vision mediated by the cones, it is the loss of these photoreceptors that results in legal blindness and poor quality of life. Cone dysfunction is usually observed due to two mechanisms: noncell-autonomous due to the secondary effect of rod death if the causative gene is specifically expressed in rods...

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Identifiers

PMID: 26383048
DOI: 10.1002/cm.21255
PMCID: PMC4715527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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