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Article

p27 Regulates the transition of beta-cells from quiescence to proliferation.

Diabetes - 1 Nov 2006

Georgia Senta, Bhushan Anil

Abstract excerpt

Diabetes results from an inadequate mass of functional beta-cells. Such inadequacy could result from loss of beta-cells due to an immune assault or the inability to compensate for insulin resistance. Thus, mechanisms that regulate the number of beta-cells will be key to understanding both the pathogenesis of diabetes and for developing therapies. In this study, we show that cell cycle regulator p27 plays a...

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Identifiers

PMID: 17065330
DOI: 10.2337/db06-0249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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