Article

Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish

2023-06-07

Abstract excerpt

Stimulation of pancreatic beta cell regeneration could be a therapeutic lead to treat diabetes. Unlike humans, the zebrafish can efficiently regenerate beta cells, notably from ductal pancreatic progenitors. To gain insight into the molecular pathways involved in this process, we established the transcriptomic profile of the ductal cells after beta cell ablation in the adult zebrafish. These data highlighted the p...

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Literature Corpus work: d7c46118-4dce-5315-91fc-c27e78d9d0c0
DOI: 10.1101/2023.06.05.543680

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