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Association between BRCA mutational status and survival in patients with breast cancer: a systematic review and meta-analysis.

Breast cancer research and treatment - 1 Apr 2021

Liu Miao, Xie Fei, Liu Miaoyu, Zhang Yi, Wang Shu

Abstract excerpt

BACKGROUND: Studies evaluating role of BRCA mutations on the survival outcomes in breast cancer (BC) patients have given confounding results and hence, in this meta-analysis, we assessed the impact of BRCA mutations on survival in BC patients. METHODS: Studies comparing survival outcomes of BC patients having BRCA mutations against wildtype BRCA phenotype were retrieved from PubMed, EMBASE, and Cochrane Library....

Topics

Breast Neoplasms
Disease-Free Survival
Female
Humans
Middle Aged
Mutation
Proportional Hazards Models
Triple Negative Breast Neoplasms

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33559780
DOI: 10.1007/s10549-021-06104-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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