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Article

[A pleiotrophin-specific siRNA and its effect on PTEN-/- MEF241 cells].

Ai zheng = Aizheng = Chinese journal of cancer - 1 Oct 2006

Hu Ying-Chun, Liu Min-Li, Li Gang, Huo Yan-Ying, Wu De-Chang

Abstract excerpt

BACKGROUND & OBJECTIVE: Pleiotrophin (Ptn), a secretive growth/differentiation factor, has diverse functions involved in cell activities, including adhesion, migration, survival, growth, and differentiation. Ptn has been suggested to be a potential target for the treatment of several types of cancer. Studies have showed that rRibozyme targeting Ptn suppresses the growth, angiogenesis, and metastasis of melanoma...

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Source

Identifiers

PMID: 17059762

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Suppression of tumorigenicity and metastasis in B16F10 cells by PTEN/MMAC1/TEP1 gene.Semantic proximity Read ↗

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