Article
TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1.
BMC molecular biology - 20 Oct 2006
Sen Siddhartha P, De Benedetti Arrigo
Abstract excerpt
BACKGROUND: The mammalian protein kinase TLK1 is a homologue of Tousled, a gene involved in flower development in Arabidopsis thaliana. The function of TLK1 is not well known, although knockout of the gene in Drosophila, or expression of a dominant negative mutant in mouse mammary cells causes loss of nuclear divisions and chromosome mis-segregation. TLK1B is a splice variant of TLK1 and it confers...
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