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Article

Association of the PTPN22/LYP gene with type 1 diabetes.

Pediatric diabetes - 1 Oct 2006

Steck Andrea K, Liu Si-Yang, McFann Kim, Barriga Katherine J, Babu Sunanda R, Eisenbarth George S, Rewers Marian J, She Jin-Xiong

Abstract excerpt

OBJECTIVES: The goal of this study was to verify the association between type 1 diabetes (T1D) and the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene in non-Hispanic whites (NHWs) and Hispanics from Colorado. SUBJECTS AND METHODS: The C1858T single-nucleotide polymorphism within the PTPN22 gene was genotyped in 753 patients with T1D ascertained from the diabetes clinic at the Barbara Davis...

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Source

Identifiers

PMID: 17054449
DOI: 10.1111/j.1399-5448.2006.00202.x

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association of the PTPN22/LYP gene with type 1 diabetes.PMID 17054449Read ↗

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Association between PTPN22 C1858T and type 1 diabetes: a replication in continental Italy.Semantic proximity Read ↗

Population-based and family-based studies on the protein tyrosine phosphatase non-receptor 22 gene polymorphism and type 1 diabetes: a meta-analysis.Semantic proximity Read ↗

Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population.Semantic proximity Read ↗

Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes.Semantic proximity Read ↗

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Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes.Semantic proximity Read ↗

A haplotype-based analysis of the PTPN22 locus in type 1 diabetes.Semantic proximity Read ↗

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.Semantic proximity Read ↗

Association of PTPN22 C1858T polymorphism and type 1 diabetes: a meta-analysis.Semantic proximity Read ↗

Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): association between a promoter polymorphism and type 1 diabetes in Asian populations.Semantic proximity Read ↗

PTPN22 gene polymorphism (C1858T) is associated with susceptibility to type 1 diabetes: a meta-analysis of 19,495 cases and 25,341 controls.Semantic proximity Read ↗

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