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Article

Association of PTPN22 C1858T polymorphism and type 1 diabetes: a meta-analysis.

Immunological investigations - 1 Jan 2012

Peng Hui, Zhou Mo, Xu Wang-Dong, Xu Ke, Zhai Yu, Li Rui, Wang Wei, Zhang Yu-Jing, Liu Shan-Shan, Pan Hai-Feng, Ye Dong-Qing

Abstract excerpt

Recently, protein tyrosine phosphatase nonreceptor 22 (PTPN22) C1858T polymorphism has been identified as a susceptibile gene for type 1 diabetes (T1D), but studies are inconsistence, In order to assess the association between PTPN22C1858T polymorphism and T1D based on different ethnicities, a meta-analysis was performed, including 26 studies, total of 16,240 patients and 17,997 controls. Meta-analysis was...

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Share to Diabetes Mellitus, Type 1
Share to PTPN22 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Polymorphism, Genetic

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Identifiers

PMID: 22429252
DOI: 10.3109/08820139.2012.664226

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of PTPN22 C1858T polymorphism and type 1 diabetes: a meta-analysis.PMID 22429252Read ↗

PTPN22 gene polymorphism (C1858T) is associated with susceptibility to type 1 diabetes: a meta-analysis of 19,495 cases and 25,341 controls.Semantic proximity Read ↗

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Association of the PTPN22 gene (+1858C/T, -1123G/C) polymorphisms with type 1 diabetes mellitus: a systematic review and meta-analysis.Semantic proximity Read ↗

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Meta-analysis of the family-based association between the PTPN22 C1858T polymorphism and type 1 diabetes.Semantic proximity Read ↗

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