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Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells

11 Aug 2004

Abstract excerpt

Clonogenic neural stem cells (NSCs) are self-renewing cells that maintain the capacity to differentiate into brain-specific cell types, and may also replace or repair diseased brain tissue. NSCs can be directly isolated from fetal or adult nervous tissue, or derived from embryonic stem cells. Here, we describe the efficient conversion of human adult bone marrow stromal cells (hMSC) into a neural stem cell-like...

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PMID: 15304527
DOI: 10.1242/jcs.01307

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