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Article

Risks of cancer due to a single BRCA1 mutation in an extended Utah kindred.

Familial cancer - 1 Jan 2007

Vogl Florian D, Badzioch Mike D, Steele Linda, Neuhausen Susan L, Goldgar David E

Abstract excerpt

OBJECTIVE: Germline mutations in the BRCA1 gene are associated with an increased risk of breast and ovarian cancer, but there is controversy about the true magnitude of these risks. Observed differences can arise from several sources, both genetic and methodological. To examine the efficiency and bias associated with different methods of risk calculation, we analyzed a single mutation in a large pedigree with...

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Source

Identifiers

PMID: 17051349
DOI: 10.1007/s10689-006-9106-8

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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