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Article

Amino acid 1-209 is essential for PDX-1-mediated repression of human CMV IE promoter activity.

Acta pharmacologica Sinica - 1 Nov 2006

Chen Jing, Chen Lei, Li Ge, Cheng Lu, Huang Yin, Zhang Jia-xin, Fan Wei-wei, Lu Da-ru

Abstract excerpt

AIM: To explore the different roles of pancreatic duodenal homeobox factors-1 (PDX-1) domains in PDX-1 mediated repression of human cytomegalovirus immediately early (CMV IE) promoter. METHODS: A series of truncated PDX-1 mutants were constructed. The binding of PDX-1 and CMV IE promoter was identified by electrophoretic mobility shift assay (EMSA). The dual-reporter assay was applied to examine the repression...

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PMID: 17049127
DOI: 10.1111/j.1745-7254.2006.00420.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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