Article
Differential expression of BDNF mRNA splice variants in mouse brain and immune cells.
Journal of neuroimmunology - 1 Jan 2007
Kruse Niels, Cetin Seray, Chan Andrew, Gold Ralf, Lühder Fred
Abstract excerpt
For the neurotrophin BDNF several splice variants were recently described. We analyzed the expression of mBDNF mRNA splice variants in cells of the immune system in comparison to the central nervous system (CNS). Whereas all splice variants are expressed in the CNS, only mBDNF 3 mRNA could be detected in primary and secondary lymphoid organs as well as in purified T cells and macrophages. After activation, only...
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