Article
A mRNA variant encoding a soluble form of 4-1BB, a member of the murine NGF/TNF receptor family.
Gene - 27 Oct 1995
Setareh M, Schwarz H, Lotz M
Abstract excerpt
The murine 4-1BB gene, encoding a member of the nerve growth factor/tumor necrosis factor (NGF/TNF) receptor family, is thought to be selectively expressed in T cells and is involved in the regulation of lymphocyte proliferation. We detected two forms of the 4-1BB mRNA by RT-PCR which were expressed in an activation-dependent pattern in splenocytes and thymocytes. cDNA sequencing showed that the smaller form was...
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