Article
A mRNA variant encoding a soluble form of 4-1BB, a member of the murine NGF/TNF receptor family.
Gene - 27 Oct 1995
Setareh M, Schwarz H, Lotz M
Abstract excerpt
The murine 4-1BB gene, encoding a member of the nerve growth factor/tumor necrosis factor (NGF/TNF) receptor family, is thought to be selectively expressed in T cells and is involved in the regulation of lymphocyte proliferation. We detected two forms of the 4-1BB mRNA by RT-PCR which were expres...
Topics
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Antigens, CD
- Base Sequence
- Blotting, Northern
- DNA Primers
- Exons
- Gene Expression
- Genetic Variation
- Lymphocyte Activation
- Mice
- Molecular Sequence Data
- Organ Specificity
- Polymerase Chain Reaction
- Protein Sorting Signals
- RNA, Messenger
- Receptors, Nerve Growth Factor