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Article

The merits of testing Hardy-Weinberg equilibrium in the analysis of unmatched case-control data: a cautionary note.

Annals of human genetics - 1 Nov 2006

Zou Guang Yong, Donner Allan

Abstract excerpt

Testing for departures from the assumption of Hardy-Weinberg equilibrium (HWE) has been widely recommended as a preliminary step in the analysis of genetic case-control studies. Some authors suggest using a two-stage procedure in which gene/disease associations are ultimately evaluated using eith...

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PMID: 17044866
DOI: 10.1111/j.1469-1809.2006.00267.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17044866-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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