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Article

Association study of G protein-coupled receptor kinase 4 gene variants with essential hypertension in northern Han Chinese.

Annals of human genetics - 1 Nov 2006

Wang Yaping, Li Biao, Zhao Weiyan, Liu Pei, Zhao Qi, Chen Shufeng, Li Hongfan, Gu Dongfeng

Abstract excerpt

To investigate the association between polymorphisms in the G protein-coupled receptor kinase 4 gene (GRK4) (R65L, A142V and A486V) and essential hypertension in northern Han Chinese, we conducted a case-control study consisting of 503 individuals with essential hypertension (HT) and 490 age-, gender-, and area-matched normotensive (NT) controls. The three GRK4 variants were genotyped by PCR-RFLP analysis. Both...

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Identifiers

PMID: 17044852
DOI: 10.1111/j.1469-1809.2006.00278.x

Genes

GRK4

Variants

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