Article
Association of G-protein-coupled receptor kinase 4 haplotypes, but not HSD3B1 or PTP1B polymorphisms, with essential hypertension.
Journal of hypertension - 1 May 2004
Speirs Helen J L, Katyk Ksenia, Kumar Natasha N, Benjafield Adam V, Wang William Y S, Morris Brian J
Abstract excerpt
OBJECTIVE: To perform association studies of polymorphisms of the potential candidate essential hypertension (HT) genes GRK4, PTP1B and HSD3B1. METHODS: Subjects consisted of 168 unrelated, Caucasian essential hypertensive (HT) patients and 312 normotensive (NT) controls. Biological power was increased by ensuring subjects in each group had parents with the same blood pressure (BP) status as theirs. Three...
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