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Article

IGF1, growth pathway polymorphisms and schizophrenia: a pooling study.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2007

Gunnell D, Lewis S, Wilkinson J, Georgieva L, Davey G Smith, Day I N M, Holly J M P, O'Donovan M C, Owen M J, Kirov G, Zammit S

Abstract excerpt

It has been hypothesized that insulin-like growth factors (IGFs) and components of the growth-hormone (GH)-IGF axis may underlie reported associations of poor fetal and childhood growth with schizophrenia. We have investigated the association of schizophrenia with 16 SNPs spanning the IGF1 gene with an inter-marker distance of approximately 2-3 kb. We also examined associations with four common functional...

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Identifiers

PMID: 17044098
DOI: 10.1002/ajmg.b.30396

Genes

IGF1
IGFBP3
IRS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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