Article
Association study in the 5q31-32 linkage region for schizophrenia using pooled DNA genotyping.
BMC psychiatry - 25 Feb 2008
Zaharieva Irina, Georgieva Lyudmila, Nikolov Ivan, Kirov George, Owen Michael J, O'Donovan Michael C, Toncheva Draga
Abstract excerpt
BACKGROUND: Several linkage studies suggest that chromosome 5q31-32 might contain risk loci for schizophrenia (SZ). We wanted to identify susceptibility genes for schizophrenia within this region. METHODS: We saturated the interval between markers D5S666 and D5S436 with 90 polymorphic microsatellite markers and genotyped two sets of DNA pools consisting of 300 SZ patients of Bulgarian origin and their 600...
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