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Article

Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.

Nature - 6 May 2004

Ozaki Kouichi, Inoue Katsumi, Sato Hiroshi, Iida Aritoshi, Ohnishi Yozo, Sekine Akihiro, Sato Hideyuki, Odashiro Keita, Nobuyoshi Masakiyo, Hori Masatsugu, Nakamura Yusuke, Tanaka Toshihiro

Abstract excerpt

Myocardial infarction (MI) has become one of the leading causes of death in the world. Its pathogenesis includes chronic formation of plaque inside the vessel wall of the coronary artery and acute rupture of the artery, implicating a number of inflammation-mediating molecules, such as the cytokin...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15129282
DOI: 10.1038/nature02502

Genes

LTA
LGALS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15129282-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.PMID 15129282Read ↗

Inflammation as a risk factor for myocardial infarction.Semantic proximity Read ↗

Genome-wide association study to identify SNPs conferring risk of myocardial infarction and their functional analyses.Semantic proximity Read ↗

Lymphotoxin-alpha and galectin-2 SNPs are not associated with myocardial infarction in two different German populations.Semantic proximity Read ↗

Polymorphisms of LTA, LGALS2, and PSMA6 genes and coronary atherosclerosis: a pathological study of 1503 consecutive autopsy cases.Semantic proximity Read ↗

Lack of association between LTA and LGALS2 polymorphisms and myocardial infarction in Japanese and Korean populations.Semantic proximity Read ↗

LGALS2 functional variant rs7291467 is not associated with susceptibility to myocardial infarction in Caucasians.Semantic proximity Read ↗

Galectin-2 3279TT variant protects against the lymphotoxin-alpha 252GG genotype associated ischaemic stroke.Semantic proximity Read ↗

Lack of association between lymphotoxin-alpha, galectin-2 polymorphisms and coronary artery disease: a meta-analysis.Semantic proximity Read ↗

Effects of lymphotoxin-alpha gene and galectin-2 gene polymorphisms on inflammatory biomarkers, cellular adhesion molecules and risk of coronary heart disease.Semantic proximity Read ↗

Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study.Semantic proximity Read ↗

Advances in the genetic basis of coronary artery disease.Semantic proximity Read ↗

Molecular genetics of coronary artery disease.Semantic proximity Read ↗

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