Article
Analysis of a natural immune response against tumor antigens in a melanoma survivor: lessons applicable to clinical trial evaluations.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2001
Yamshchikov G, Thompson L, Ross W G, Galavotti H, Aquila W, Deacon D, Caldwell J, Patterson J W, Hunt D F, Slingluff C L
Abstract excerpt
The long-term survival of some patients with metastatic melanoma may be attributable in part to cellular immune responses to melanoma antigens. However, little is known about the level of CTL reactivity in vivo that is required for immunological control of tumor progression. In the present report, T-cell responses were evaluated with lymphocytes obtained from tumor-involved nodes and peripheral blood of a...
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