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Article

No influence of 3435C>T ABCB1 (MDR1) gene polymorphism on risk of adult acute myeloid leukemia and P-glycoprotein expression in blast cells.

Therapeutic drug monitoring - 1 Oct 2006

Jamroziak Krzysztof, Balcerczak Ewa, Cebula Barbara, Janus Agnieszka, Mirowski Marek, Robak Tadeusz

Abstract excerpt

Inherited differences in xenobiotic transport and metabolism may play an important role in the development of adult acute myeloid leukemia (AML) and response to the chemotherapy. An ATP-binding cassette (ABC) family transporter P-glycoprotein (P-gp or ABCB1), encoded by ABCB1 (MDR1) gene, is involved in the protection against xenobiotics and multi-drug resistance. The aim of this study was to investigate the...

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Identifiers

PMID: 17038891
DOI: 10.1097/01.ftd.0000245770.75097.3f

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No influence of 3435C>T ABCB1 (MDR1) gene polymorphism on risk of adult acute myeloid leukemia and P-glycoprotein expression in blast cells.PMID 17038891Read ↗

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