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Article

C3435T polymorphism of the MDR1 gene is not associated with P-glycoprotein function of leukemic blasts and clinical outcome in patients with acute myeloid leukemia.

Leukemia research - 1 Oct 2008

Hur Eun-Hye, Lee Je-Hwan, Lee Michael Jinpyo, Choi Seong-Jun, Lee Jung-Hee, Kang Mun Jung, Seol Miee, Jang Yae Eun, Lee Hee-Jung, Kang Ip-Sol, Shim Soo-Kyung, Ryu Seong-Gil, Kang Young-Ah, Lee Young-Shin, Park Chan-Jeoung, Chi Hyun-Sook, Lee Kyoo-Hyung

Abstract excerpt

We investigated the association between the MDR1 C3435T polymorphism and P-glycoprotein function of leukemic blasts as well as clinical outcomes in 200 patients with AML, excluding the M3 subtype. The CC, CT and TT genotype frequencies of the C3435T polymorphism among patients were 71, 93 and 36,...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18272218
DOI: 10.1016/j.leukres.2007.12.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18272218-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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