Article
GenoChip CYP2D6 macroarray as a method to genotype for CYP2D6 variants: results of a validation study in a Caucasian population.
Pharmacogenomics - 1 Jan 2015
Bank Paul C D, Swen Jesse J, Guchelaar Henk-Jan, van der Straaten Tahar
Abstract excerpt
AIM: The aim of this study was to investigate the concordance between the novel GenoChip CYP2D6 macroarray and the AmpliChip, which is considered the gold standard in CYP2D6 genotyping. MATERIALS & METHODS: Germline DNA of 200 patients was genotyped with both the AmpliChip and the GenoChip CYP2D6 macroarray. RESULTS: One hundred and ninety-eight samples (99%) showed concordance. In two discordant samples the...
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