Article
Rapid genotyping of CYP2D6, CYP2C19 and TPMT polymorphisms by primer extension reaction in a dipstick format.
Analytical and bioanalytical chemistry - 1 Nov 2007
Litos Ioannis K, Emmanouilidou Evaggelia, Glynou Kyriaki M, Laios Eleftheria, Ioannou Penelope C, Christopoulos Theodore K, Kampa Marilena, Castanas Elias, Gravanis Achille
Abstract excerpt
In recent years an increasing amount of interest has been directed at the study and routine testing of polymorphisms responsible for variations in drug metabolism. Most of the current methods involve either time-consuming electrophoresis steps or specialized and expensive equipment. In this context, we have developed a rapid, simple and robust method for genotyping of CYP2D6*3, CYP2D6*4, CYP2C19*2, CYP2C19*3 and...
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