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Article

Sarcoma Derived from Cultured Mesenchymal Stem Cells

12 Oct 2006

Abstract excerpt

To study the biodistribution of MSCs, we labeled adult murine C57BL/6 MSCs with firefly luciferase and DsRed2 fluorescent protein using nonviral Sleeping Beauty transposons and coinfused labeled MSCs with bone marrow into irradiated allogeneic recipients. Using in vivo whole-body imaging, luciferase signals were shown to be increased between weeks 3 and 12. Unexpectedly, some mice with the highest luciferase...

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PMID: 17038675
DOI: 10.1634/stemcells.2005-0620

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