Article

Somatic gene delivery for flexible <i>in vivo</i> modeling of high-risk sarcoma

2024-02-01

Abstract excerpt

<h4>ABSTRACT</h4> A particular challenge hampering therapeutic advancements for high-risk sarcoma patients is the broad spectrum of molecularly distinct sarcoma entities and the corresponding lack of suitable model systems to recapitulate and study these diseases. To overcome this predicament, we developed a novel genetically-controlled, yet versatile mouse modeling platform allowing delivery of different genetic...

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Literature Corpus work: de2e8dc5-22a1-5cda-8af6-5684839b23e5
DOI: 10.1101/2024.01.30.577924

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