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Article

Animal models of soft-tissue sarcoma

17 Aug 2010

Abstract excerpt

Soft-tissue sarcomas (STSs) are rare mesenchymal tumors that arise from muscle, fat and connective tissue. Currently, over 75 subtypes of STS are recognized. The rarity and heterogeneity of patient samples complicate clinical investigations into sarcoma biology. Model organisms might provide traction to our understanding and treatment of the disease. Over the past 10 years, many successful animal models of STS...

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PMID: 20713645
DOI: 10.1242/dmm.005223

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