Article
[Four new cases with WT1 gene mutations in Chinese patients with Wilms' tumor].
Zhonghua er ke za zhi = Chinese journal of pediatrics - 1 Oct 2009
Jiang Ye-ping, Shen Ying, Sun Ning, Wang Hui
Abstract excerpt
OBJECTIVE: Wilms' tumor (WT) is the most common malignant renal tumor in childhood. The WT1 gene located at 11p13 was identified in 1990 as a tumor suppressor gene important in the development in WT. The WT1 gene consists of 10 exons, with exons 1 to 6 encoding an N-terminal proline- and glutamin...
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