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Article

Polymorphisms of CYP2A6 and its practical consequences.

British journal of clinical pharmacology - 1 Oct 2001

Raunio H, Rautio A, Gullstén H, Pelkonen O

Abstract excerpt

CYP2A6 is an hepatic enzyme predominantly with some expression in specialized extrahepatic cell types. The CYP2A6 enzyme has a somewhat restricted active site, accepting only a few xenobiotics as substrates. Interest in CYP2A6 has risen considerably after nicotine and some tobacco specific nitrosamines were established as high-affinity substrates for this enzyme. Recently, the organization and structures of the...

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Identifiers

PMID: 11678779
DOI: 10.1046/j.0306-5251.2001.01500.x
PMCID: PMC2014580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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