Article
Plasticity of a critical antigenic determinant in the West Nile virus NY99 envelope protein domain III.
Virology - 1 Sept 2016
Plante Jessica A, Torres Maricela, Huang Claire Y-H, Beasley David W C
Abstract excerpt
West Nile virus (WNV) is a mosquito-borne flavivirus that causes febrile illness, encephalitis, and occasionally death in humans. The envelope protein is the main component of the WNV virion surface, and domain III of the envelope protein (EIII) is both a putative receptor binding domain and a target of highly specific, potently neutralizing antibodies. Envelope E-332 (E-332) is known to have naturally occurring...
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