Article
Glutathione S-transferase polymorphisms and onset age in alpha-synuclein A53T mutant Parkinson's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2007
Golbe Lawrence I, Di Iorio Giuseppe, Markopoulou Katerina, Athanassiadou Aglaia, Papapetropoulos Spiridon, Watts Ray L, Vance Jeffery M, Bonifati Vincenzo, Williams Tanishia A, Spychala John R, Stenroos E Scot, Johnson Williams G
Abstract excerpt
Monogenic forms of Parkinson's disease (PD) provide an opportunity to examine mechanisms underlying phenotypic variation. Glutathione S-transferase (GST) has detoxification and antioxidative functions. To screen genetic variations in GST for an effect on the onset age (OA) of PD, we typed seven c...
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