Article
Glutathione S-transferase polymorphism in Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2000
Rahbar A, Kempkes M, Müller T, Reich S, Welter F L, Meves S, Przuntek H, Bolt H M, Kuhn W
Abstract excerpt
Glutathione S-transferases (GSTs) are involved in the detoxification of endogenous or exogenous toxins, which may play a role in the pathogenesis of Parkinson's disease. We genotyped the Glutathione-S-Transferase isoenzymes GSTM1 and GSTT1 by polymerase chain reaction in order to evaluate different gene polymorphisms of these isoenzymes in 149 parkinsonian and 99 control subjects. No differences appeared between...
Read the complete abstract on PubMedTopics
- Adult
- Aged
- Aged, 80 and over
- Female
- Gene Frequency
- Genotype
- Glutathione Transferase
