Article
Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype.
The Journal of clinical endocrinology and metabolism - 1 Jan 2007
Goodarzi Mark O, Taylor Kent D, Guo Xiuqing, Hokanson John E, Haffner Steven M, Cui Jinrui, Chen Yii-Der I, Wagenknecht Lynne E, Bergman Richard N, Rotter Jerome I
Abstract excerpt
CONTEXT: Prior studies of Mexican Americans described association of lipoprotein lipase (LPL) gene haplotypes with insulin sensitivity/resistance and atherosclerosis. The most common haplotype (haplotype 1) was protective, whereas the fourth most common haplotype (haplotype 4) conferred risk for insulin resistance and atherosclerosis. OBJECTIVE: In this study of Hispanics in the Insulin Resistance Atherosclerosis...
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