Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity.

The Journal of clinical endocrinology and metabolism - 1 Aug 2005

Goodarzi Mark O, Wong Howard, Quiñones Manuel J, Taylor Kent D, Guo Xiuqing, Castellani Lawrence W, Antoine Heath J, Yang Huiying, Hsueh Willa A, Rotter Jerome I

Abstract excerpt

CONTEXT: Haplotypes comprising six single nucleotide polymorphisms (SNPs) (intron 7 to intron 9) of the lipoprotein lipase (LPL) gene appear to influence risk for atherosclerosis and insulin resistance in Mexican-Americans. OBJECTIVE: Based on rodent studies, we hypothesized that these haplotypes are in linkage disequilibrium with functional variants in the 3' untranslated region of LPL, which is encoded by exon...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Arteriosclerosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heparin

Share to Insulin Resistance

Share to Introns

Share to Linkage Disequilibrium

Share to Lipoprotein Lipase

Share to Mexican Americans

Source

Identifiers

PMID: 15928243
DOI: 10.1210/jc.2005-0389

Genes

LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity.PMID 15928243Read ↗

Determination and use of haplotypes: ethnic comparison and association of the lipoprotein lipase gene and coronary artery disease in Mexican-Americans.Semantic proximity Read ↗

Haplotypes in the lipoprotein lipase gene influence high-density lipoprotein cholesterol response to statin therapy and progression of atherosclerosis in coronary artery bypass grafts.Semantic proximity Read ↗

Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels.Semantic proximity Read ↗

Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype.Semantic proximity Read ↗

Association between lipoprotein lipase (LPL) gene and blood lipids: a common variant for a common trait?Semantic proximity Read ↗

Association of endothelial lipase gene (LIPG) haplotypes with high-density lipoprotein cholesterol subfractions and apolipoprotein AI plasma levels in Japanese Americans.Semantic proximity Read ↗

Analysis of lipoprotein lipase haplotypes reveals associations not apparent from analysis of the constituent loci.Semantic proximity Read ↗

Three polymorphisms associated with low hepatic lipase activity are common in African Americans.Semantic proximity Read ↗

DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene.Semantic proximity Read ↗

Identification of promoter variants in baboon endothelial lipase that regulate high-density lipoprotein cholesterol levels.Semantic proximity Read ↗

A novel LPL intronic variant: g.18704C>A identified by re-sequencing Kuwaiti Arab samples is associated with high-density lipoprotein, very low-density lipoprotein and triglyceride lipid levels.Semantic proximity Read ↗

Lipoprotein lipase is a gene for insulin resistance in Mexican Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.