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Article

Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development.

Nature neuroscience - 1 Jan 2005

Rosso Silvana B, Sussman Daniel, Wynshaw-Boris Anthony, Salinas Patricia C

Abstract excerpt

Dendritic arborization is required for proper neuronal connectivity. Rho GTPases have been implicated in the regulation of dendrite development. However, the signaling pathways that impinge on these molecular switches remain poorly understood. Here we show that Wnt7b, which is expressed in the mouse hippocampus, increases dendritic branching in cultured hippocampal neurons. This effect is mimicked by the...

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PMID: 15608632
DOI: 10.1038/nn1374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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