Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain.

European journal of epidemiology - 1 Jan 2006

Portolés Olga, Sorlí José Vicente, Francés Francesc, Coltell Oscar, González Jose I, Sáiz Carmen, Corella Dolores

Abstract excerpt

There are no good genetic markers for incorporating the study of genetic susceptibility to obesity in epidemiological studies. In animal models, the leptin (LEP) and the leptin receptor (LEPR) genes have been shown to be very important in obesity because leptin functions as a negative feedback signal in regulating body-weight through reducing food intake and stimulating energy expenditure. In humans, several...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Leptin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Obesity

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Receptors, Cell Surface

Share to Receptors, Leptin

Source

Identifiers

PMID: 17031518
DOI: 10.1007/s10654-006-9045-6

Genes

LEP
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain.PMID 17031518Read ↗

Relationship Between Leptin G2548A and Leptin Receptor Q223R Gene Polymorphisms and Obesity and Metabolic Syndrome Risk in Tunisian VolunteersSemantic proximity Read ↗

LEPR p.Q223R Polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients.Semantic proximity Read ↗

Leptin G-2548A and leptin receptor Q223R gene polymorphisms are not associated with obesity in Romanian subjects.Semantic proximity Read ↗

LEPR p.Q223R, beta3-AR p.W64R and LEP c.-2548G>A gene variants in obese Brazilian subjects.Semantic proximity Read ↗

Association of leptin receptor gene Q223R polymorphism on lipid profiles in comparison study between obese and non-obese subjects.Semantic proximity Read ↗

p.Q223R leptin receptor polymorphism associated with obesity in Brazilian multiethnic subjects.Semantic proximity Read ↗

LEP -2548G>A Polymorphism of the Leptin Gene and Its Influence on the Lipid Profile in Obese Individuals.Semantic proximity Read ↗

Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil.Semantic proximity Read ↗

Leptin and Leptin receptor polymorphisms, plasma Leptin levels and obesity in Tunisian volunteers.Semantic proximity Read ↗

Genetics of leptin and obesity: a HuGE review.Semantic proximity Read ↗

Association with leptin gene C.-2548 G>A polymorphism, serum leptin levels, and body mass index in Turkish obese patients.Semantic proximity Read ↗

Leptin and leptin receptor polymorphisms are related to body mass index in a Turkish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.