LEPR p.Q223R Polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients.

doi:10.1016/j.arcmed.2009.02.008

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Article

LEPR p.Q223R Polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients.

Archives of medical research - 1 Apr 2009

Ben Ali Samir, Kallel Amani, Sediri Yousra, Ftouhi Bouchra, Feki Moncef, Slimene Hedia, Jemaa Riadh, Kaabachi Naziha

Abstract excerpt

BACKGROUND AND AIMS: The leptin receptor (LEPR) plays a crucial role in the regulation of body weight. Several common polymorphisms have been described in the human LEPR gene including the p.Q223R polymorphism (rs1137101). The association of this polymorphism with obesity or related metabolic phenotypes has been controversial. The aim of this study was to investigate the impact of the LEPR p.Q223R polymorphism on...

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PMID: 19427969
DOI: 10.1016/j.arcmed.2009.02.008

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LEPR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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