Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leptin and Leptin receptor polymorphisms, plasma Leptin levels and obesity in Tunisian volunteers.

International journal of experimental pathology - 1 Jun 2018

Nesrine Zayani, Haithem Hamdouni, Imen Boumaiza, Fadoua Neffati, Asma Omezzine, Fadhel Najjar Mohamed, Ali Bouslama

Abstract excerpt

Adipose tissue is an important endocrine organ that secretes a number of adipokines, like Leptin (LEP). The aim this study was to investigate the prevalence of single nucleotide polymorphisms in LEP gene (LEP 3'UTR A/C, -2548 G/A) and LEPR (K109R and Q223R) and their association with Leptin level and obesity. We recruited 169 non-obese (body mass index [BMI] = 24.51-3.69 kg/m2 ) and 160 obese (BMI = 36-4.78 kg/m2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Haplotypes

Share to Leptin

Share to Obesity

Share to Receptors, Leptin

Share to Tunisia

Source

Open in PubMed Open full text

Identifiers

PMID: 29893028
DOI: 10.1111/iep.12271
PMCID: PMC6104422

Genes

LEP
LEPR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leptin and Leptin receptor polymorphisms, plasma Leptin levels and obesity in Tunisian volunteers.PMID 29893028Read ↗

Relationship Between Leptin G2548A and Leptin Receptor Q223R Gene Polymorphisms and Obesity and Metabolic Syndrome Risk in Tunisian VolunteersSemantic proximity Read ↗

Association of G-2548A LEP polymorphism with plasma leptin levels in Tunisian obese patientsSemantic proximity Read ↗

Association with leptin gene C.-2548 G>A polymorphism, serum leptin levels, and body mass index in Turkish obese patients.Semantic proximity Read ↗

LEPR p.Q223R Polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients.Semantic proximity Read ↗

Leptin and leptin receptor gene polymorphisms and their association with plasma leptin levels and obesity in a multi-ethnic Malaysian suburban population.Semantic proximity Read ↗

Leptin G-2548A and leptin receptor Q223R gene polymorphisms are not associated with obesity in Romanian subjects.Semantic proximity Read ↗

Leptin receptor gene polymorphisms are associated with adiposity and metabolic alterations in Brazilian individualsSemantic proximity Read ↗

Association between Leptin gene polymorphisms and plasma leptin level in three consanguineous families with obesity.Semantic proximity Read ↗

The -2548G/A LEP polymorphism is associated with blood pressure in Tunisian obese patients.Semantic proximity Read ↗

-2548G>A LEP Polymorphism Is Positively Associated with Increased Leptin and Glucose Levels in Obese Saudi Patients Irrespective of Blood Pressure StatusSemantic proximity Read ↗

A study of leptin and its gene 2548 G/A Rs7799039 single-nucleotide polymorphisms in Egyptian children: A single-center experience.Semantic proximity Read ↗

Leptin Rs7799039 polymorphism is associated with type 2 diabetes mellitus Egyptian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.