Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Sept 2002

Mattevi V S, Zembrzuski V M, Hutz M H

Abstract excerpt

OBJECTIVE: To investigate associations of polymorphisms in the LEP, LEPR and NPY genes with obesity-related traits in a Brazilian population of European descent. METHODS: A total of 183 women and 153 men (mean body mass index (BMI), 26.1+/-4.8 kg/m(2)) were genotyped using the PCR-RFLP procedure for the LEP A19G, LEPR Gln223Arg, LEPR PRO1019pro and NPY Leu7Pro polymorphisms. Frequencies were compared among...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Body Constitution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Brazil

Share to Gene Frequency

Share to Leptin

Share to Obesity

Share to Signal Transduction

Source

Identifiers

PMID: 12187394
DOI: 10.1038/sj.ijo.0802067

Genes

LEPR
NPY
LEP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil.PMID 12187394Read ↗

Polymorphisms of leptin-melanocortin system genes associated with obesity in an adult population from BarranquillaSemantic proximity Read ↗

p.Q223R leptin receptor polymorphism associated with obesity in Brazilian multiethnic subjects.Semantic proximity Read ↗

LEPR p.Q223R, beta3-AR p.W64R and LEP c.-2548G>A gene variants in obese Brazilian subjects.Semantic proximity Read ↗

Leptin receptor gene polymorphisms are associated with adiposity and metabolic alterations in Brazilian individualsSemantic proximity Read ↗

LEPR p.Q223R Polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients.Semantic proximity Read ↗

Association of leptin receptor gene Q223R polymorphism on lipid profiles in comparison study between obese and non-obese subjects.Semantic proximity Read ↗

Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain.Semantic proximity Read ↗

Genetics of leptin and obesity: a HuGE review.Semantic proximity Read ↗

Sex-specific association between leptin receptor polymorphisms and leptin levels and BMI in healthy adolescents.Semantic proximity Read ↗

Association analysis of the Gln223Arg polymorphism in the human leptin receptor gene, and traits related to obesity in Mexican adolescents.Semantic proximity Read ↗

[Meta-analysis on the relationship between leptin receptor Gln223Arg and Pro1019Pro gene polymorphism and obesity in the Chinese population].Semantic proximity Read ↗

Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.