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Article

Differential patterns of spinal cord pathology induced by MP4, MOG peptide 35-55, and PLP peptide 178-191 in C57BL/6 mice.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jun 2011

Kuerten Stefanie, Gruppe Traugott L, Laurentius Laura-Maria, Kirch Christiane, Tary-Lehmann Magdalena, Lehmann Paul V, Addicks Klaus

Abstract excerpt

In this study we demonstrate that experimental autoimmune encephalomyelitis (EAE) induced by the MBP-PLP fusion protein MP4, MOG peptide 35-55, or PLP peptide 178-191 in C57BL/6 mice, respectively, displays distinct features of CNS pathology. Major differences between the three models resided in (i) the region-/tract-specificity and disseminated nature of spinal cord degeneration, (ii) the extent and kinetics of...

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Source

Identifiers

PMID: 21569091
DOI: 10.1111/j.1600-0463.2011.02744.x

Genes

MOG
MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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