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Article

The long extra arms of human tRNA(Ser)Secand tRNASerfunction as major identity elements for serylation in an orientation-dependent, but not sequence-specific manner

1 Jan 1993

Abstract excerpt

Selenocysteine tRNA [tRNA((Ser)Sec)] is charged with serine by the same seryl-tRNA synthetase (SerRS) as the canonical serine tRNAs. Using site-directed mutagenesis, we have introduced a series of mutations into human tRNA((Ser)Sec) and tRNA(Ser) in order to study the identity elements of tRNA((Ser)Sec) for serylation and the effect of the orientation of the extra arm. Our results show that the long extra arm is...

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Identifiers

PMID: 8284203
DOI: 10.1093/nar/21.24.5589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The long extra arms of human tRNA(Ser)Secand tRNASerfunction as major identity elements for serylation in an orientation-dependent, but not sequence-specific mannerPMID 8284203Read ↗

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