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Article

Use of epithelial cell cultures for studies on the mechanism of transformation by chemical carcinogens.

In vitro - 1 Jan 2000

Weinstein I B, Yamaguchi N, Gebert R, Kaighn M E

Abstract excerpt

Evidence is reviewed for and against four major theories of chemical carcinogenesis. The development of several normal and transformed epithelial cell lines which should be useful for the analysis of this problem is described. The detection of RNA viral particles in cells transformed with chemical carcinogens is a recurrent finding in studies from our own and other laboratories, but the significance of these...

Topics

Carcinogens
Carcinoma, Hepatocellular
Cell Differentiation
Cell Transformation, Neoplastic
Cells, Cultured
Epithelial Cells
Epithelium
Liver Neoplasms
Mutation
Oncogenic Viruses
Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virus Replication

Source

Identifiers

PMID: 170195
DOI: 10.1007/BF02615421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-170195-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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