Molecular genetic findings in LRRK2 American, Canadian and German families.

doi:10.1007/978-3-211-45295-0_35

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Article

Molecular genetic findings in LRRK2 American, Canadian and German families.

Journal of neural transmission. Supplementum - 1 Jan 2006

Gasser T

Abstract excerpt

A locus for a dominant form of PD has been mapped to the pericentromeric region of chromosome 12 in a Japanese family. We have confirmed linkage in two families of European ancestry and identified mutations in the gene for LRRK2 in these two and four additional families with dominantly inherited...

Topics

Canada
Genetic Linkage
Germany
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Mutation
Parkinson Disease
Protein Serine-Threonine Kinases
United States

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