Article
Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations.
Oncology reports - 1 Nov 2006
Semczuk Andrzej, Lorenc Anna, Putowski Lechoslaw, Futyma Konrad, Bryk Jaroslaw, Miotla Pawel, Bartnik Ewa
Abstract excerpt
Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by EC. mtDNA mutations were detected both in early (3/32; 9%) and in advanced (1/8; 12%) stages of uterine tumors. However, patients carrying the mtDNA mutations or the...
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