Article
Mitochondrial Dysfunctions in Type I Endometrial Carcinoma: Exploring Their Role in Oncogenesis and Tumor Progression.
International journal of molecular sciences - 17 Jul 2018
Musicco Clara, Cormio Gennaro, Pesce Vito, Loizzi Vera, Cicinelli Ettore, Resta Leonardo, Ranieri Girolamo, Cormio Antonella
Abstract excerpt
Type I endometrial cancer (EC) is the most common form of EC, displaying less aggressive behavior than type II. The development of type I endometrial cancer is considered a multistep process, with slow progression from normal endometrium to hyperplasia, the premalignant form, and endometrial cancer as a result of an unopposed estrogenic stimulation. The role of mitochondria in type I EC tumor progression and...
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