Article
FGF signaling delineates the cardiac progenitor field in the simple chordate, Ciona intestinalis.
Genes & development - 1 Oct 2006
Davidson Brad, Shi Weiyang, Beh Jeni, Christiaen Lionel, Levine Mike
Abstract excerpt
Comprehensive gene networks in Ciona intestinalis embryos provide a foundation for characterizing complex developmental processes, such as the initial phases of chordate heart development. The basic helix-loop-helix regulatory gene Ci-Mesp is required for activation of cardiac transcription factors. Evidence is presented that Ci-Ets1/2, a transcriptional effector of receptor tyrosine kinase (RTK) signaling, acts...
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