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Article

Genes related to iron metabolism and susceptibility to Alzheimer's disease in Basque population.

Neurobiology of aging - 1 Dec 2007

Blázquez L, De Juan D, Ruiz-Martínez J, Emparanza J I, Sáenz A, Otaegui D, Sistiaga A, Martínez-Lage P, Lamet I, Samaranch L, Buiza C, Etxeberria I, Arriola E, Cuadrado E, Urdaneta E, Yanguas J, López de Munain A

Abstract excerpt

Alzheimer's disease (AD) is the most common dementing disorder and presents with a progressive and irreversible cognitive decline of gradual onset. To date, several reports have involved iron in AD physiopathology. In this study, we have analysed TFC2 variant and HFE mutations (H63D and C282Y) in 211 AD patients and 167 controls recruited from an area of the Basque Country. Furthermore, we have studied APOE...

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Source

Identifiers

PMID: 17011669
DOI: 10.1016/j.neurobiolaging.2006.08.009

Genes

APOE
HFE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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