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Article

HFE variants, APOE and Alzheimer's disease: findings from the population-based Rotterdam study.

Neurobiology of aging - 1 Feb 2009

Alizadeh B Z, Njajou O T, Millán M R, Hofman A, Breteler M M, van Duijn C M

Abstract excerpt

Iron is a reactive oxygen species and has been implicated in the pathogenesis of Alzheimer's disease (AD). In a population-based cohort study, including 268 incident AD patients and 2079 control individuals, we investigated the influence of the HFE C282Y and H63D variants and the apolipoprotein E...

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Source

Identifiers

PMID: 17628213
DOI: 10.1016/j.neurobiolaging.2007.05.026

Genes

APOE
HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17628213-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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